Need for new medical drugs in Ireland

Certain new drugs have been found to be very effective in the treatment of CFS in the USA, Canada, Mexico and Belgium. Most Irish doctors and the Irish Medical Council have never heard about these new CFS drugs. Their knowledge on these matters is 10 -15 years out of date. This lack of knowledge means CFS patients are being deprived of treatments which could greatly improve their condition and bring about recovery in a majority of cases. Many CFS patients have been waiting several years and decades, they cannot continue waiting, people are dying of CFS and the serious health complications caused by CFS.

The Irish government should approve the following medical drugs and supplements for ME / CFS treatment on the basis of successful trials and treatments in Canada, the USA, Mexico and Belgium.

1. Ampligen   produced by Hemispherx Biopharma, Inc   http://www.hemispherx.net
   Ampligen is being tested by the FDA in the USA for CFS and AIDS cases. Ampligen is approved for CFS and AIDS treatment in Canada.
   Research articles    
   -  http://www.hemispherx.net/content/rnd/abstract_scientfic.htm
   -  http://www.hemispherx.net/content/rnd/drug_candidates.htm
   -  What is Ampligen ?
   - ' Chronic Fatigue Syndrome :  A Biological Approach '  by Patrick Englebienne and Dr. Kenny De Meirleir 

    

2. Elastase inhibitors
   Use of leukocyte elastase inhibitors to treat patients with CFS as well as MS due to its impact on RnaseL and STAT1.

   -	Cefoperazone  (Pfizer Pharmaceuticals, trade name Cefobid)  -  Dr. Kenny De Meirleir has shown that it can block the elastase activity which is involved in destroying the immune systems of CFS patients
   -	Beta-lactam based antibiotics act as leukocyte elastase inhibitors
   -	Boswellia  (Boswellic acid)
   Research articles
   -	Total Exposure - Expanded Model for RNase L Fragmentation in CFS Uncovered; The National CFIDS Foundation Announces the Use of Elastase Inhibitors as a Potential Treatment for CFS Patients (2003)
   -	' Chronic Fatigue Syndrome :  A Biological Approach '  by Patrick Englebienne and Dr. Kenny De Meirleir

   
   

3. MG132  to stop STAT1-alpha cleavage and degradation.
   Research articles   
   -  STAT1-alpha and p53 Deficiencies are Found in Patients with Chronic Fatigue Syndrome (2003)
   - ' Chronic Fatigue Syndrome :  A Biological Approach '  by Patrick Englebienne and Dr. Kenny De Meirleir 
   
   

4. Acclydine Therapy recommended by Dr. De Meirleir  (top CFS doctor and researcher)
   Research articles
   - ' Chronic Fatigue Syndrome :  A Biological Approach '  by Patrick Englebienne and Dr. Kenny De Meirleir 
   
   

5. Isoprinosine to strengthen the TH1 part of the immune system, highly recommended by Dr. Paul Cheney (Dr. Paul Cheney has successfully treated hundreds of CFS patients in the USA)
   Research articles
   Lecture given by Dr. Paul Cheney
   
   
   

6. Dr. Paul Cheney's recommendations  (Dr. Paul Cheney has successfully treated hundreds of CFS patients in the USA) 
   For sleep -  Klonopin (generic: clonazepam) and Doxepin Elixir (10mg/ml) and Magnesium 500mg.
   For mitochondria function and immune system  - Undenatured whey protein, Reduced L-Glutathione, B-12 Injections, Kutapressin.
   See complete medical protocol at : http://virtualhometown.com/dfwcfids/medical/cheney.html
   
   

7. Compulsory mercury tests for all CFS patients. Mercury is highly toxic to humans even in small quantities. Research has shown a link between high levels of mercury in the body and ME / CFS . Mercury can interfere with mitochondria function and deplete glutathione levels both of which are indicated in CFS. Mercury detoxification has led to some CFS recoveries.  
   Research articles:
   
   

8. Scientific trials of a strong anti-viral protocol for CFS patients  -  a combination of Transfer Factor, Coconut oil, Olive Leaf extract and MGN-3. These have no known side-effects. If these trials are successful they should be made available on prescription for all CFS patients.
   Research articles   
   -  www.chronicfatiguesupport.com
   
   

9. Treat Sleep problem and provide Neuroprotection 

Dr. Paul Cheney recommends shifting the brain from excess NMDA activity to GABA activity. GABA facilitates deep sleep and a healing state. Medical research shows that certain neurotransmitters are involved in sleep - GABA, Serotonin and Melatonin. CFS patients have been found to be deficient in one or two of these neurotransmitters. Medical treatment of this problem involves increasing the activity of these neurotransmitters in the brain. A medical doctor should closely supervise sleep or neurotransmitter therapy.
Dr. Paul Cheney recommends 2-3 of the following GABA enhancers:

A.  Stimulate GABA in the brain:
A medical doctor should closely supervise this sleep or neurotransmitter therapy. Your medical doctor should specify the combination of drugs, supplements and herbs below you should take for sleep purposes.

B. Stimulation of Serotonin in the brain and nervous system:
A medical doctor should closely supervise this sleep or neurotransmitter therapy.

Some medical drugs gently increase Serotonin levels in the brain. Molipaxin 75 -100mg  or  Doxepin Elixir (10mg/ml)  1 hour before bed-time.
OR
5-HTP 200mg, 2 hours before bedtime at night. Take on an empty stomach.

Tryptophan rich Foods
Take tryptophan-rich snack(s) during the day and before bed-time.
turkey, milk, avocado, banana, wheatgerm, pumpkin seeds, chicken, tofu.
Tryptophan is converted into Serotonin in the brain.
and
Take vitamin B-Complex and Fish oils / Omega-3 oils. This helps convert Tryptophan into Serotonin in the brain.
and
Get 8-10 hours of direct sunlight every day. In Winter use a special light box. Include walking and stretching in the direct sunlight. Sunlight stimulates the production of Serotonin in the brain. Walking and Stretching improves nerve conduction.

C.  Stimulate Melatonin in the brain:
A medical doctor should closely supervise this sleep or neurotransmitter therapy.
Melatonin tablets / powder 5 - 10mg, 1 hour before bed-time

Scientific / Medical research articles concerning increasing GABA, Serotonin, Melatonin activity for solving sleep problems in CFS

-  http://virtualhometown.com/dfwcfids/medical/cheney.html  (Dr. Paul Cheney's recommendations)

-  www.chronicfatiguesupport.com

- Go to the global database of scientific research : http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed and type in the words 
"sleep"+"chronic fatigue syndrome"   -  then view / save the results
"gaba"+"chronic fatigue syndrome"   -  then view / save the results
"serotonin"+"chronic fatigue syndrome"   -  then view / save the results
"melatonin"+"chronic fatigue syndrome"   -  then view / save the results
for a full listing of scientific research worldwide
Note: You could also use the words "chronic fatigue and immune dysfunction" or "M.E." or "myalgic encephalomyelitis" as these are other other names for the illness.

- Go to the Google search engine and type in the words 
"sleep"+"chronic fatigue syndrome"   -  then view / save the results
"gaba"+"chronic fatigue syndrome"   -  then view / save the results
"serotonin"+"chronic fatigue syndrome"   -  then view / save the results
"melatonin"+"chronic fatigue syndrome"   -  then view / save the results
for an additional listing of scientific research worldwide
Note: You could also use the words "chronic fatigue and immune dysfunction" or "M.E." or "myalgic encephalomyelitis" as these are other other names for the illness.

-  www.keephope.net 
-  http://www.diagnose-me.com/ta-q.html
-  www.remedyfind.com
-  Chronic Fatigue, Fibromyalgia and Lyme disease  (2nd Edition) by Burton Goldberg and Larry Trivieri

A nation's health should be seen by governments as an investment not a cost ; indeed an investment which can reduce economic costs and increase overall economic revenues and productivity over the medium to long-term.

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